Biopharmaceutical companies: 4 Factors to Consider for the selection of your Biologics CDMO Partner

In recent years, there has been a notable increase in the number of therapeutic molecules. This increase has led to a corresponding increase in the number of CDMOs like us. With so many CDMOs to choose from, it is crucial for biopharmaceutical companies to carefully consider their selection criteria.   Finding the Right Biologics CDMO Partner  To ensure that you select the right biologics CDMO partner for your project, it’s important to ask yourself: Will you be working with the CDMO...
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Oligofastx project, development of RNA-based therapeutics

53Biologics participates in the OLIGOFASTX project. This project aims to create a comprehensive platform to facilitate and contribute to the accelerated development of oligonucleotide-based therapies in Spain. OLIGOFASTX is a multidisciplinary consortium led by Sylentis (PharmaMar Group) and in which other companies such as Nanovex Biotechnologies, ARTHEx Biotech, Aptus Data Labs, aptaTargets and Nostrum Biodiscovery participate in addition to 53Biologics. 53Biologics participates in th...
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Which Are Better? Biologics or Small Molecule Drugs?

So to decide which is the best option in medicine and biopharma between biologics or small molecule drugs, we have to consider many factors. But let´s start from the beginning.  What Is a Small Molecule Drug?  Small molecule drugs are typically derived from natural compounds produced by plants, fungi and bacteria or are designed to imitate them. These drugs use biochemical processes to prevent or treat diseases. They are highly effective as allosteric modulators and enzyme inhibitors, and are...
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Biologics CDMO: Why You Need One

The rapidly growing market for biologics has made contract biologics development and production corporations (CDMO) more essential. The complexity inherent in the development of biologics and their mass production for sale makes it impossible for biopharmaceutical and pharmaceutical companies to perform the process in-house. What Is a Biologics CDMO Company?  A contract biologics development and manufacturing company (CDMO) provides medical biologics development and manufacturing services for p...
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Accelerating Biologics Manufacturing

In today’s pharmaceutical and biotechnology industry, the focus is on reducing development time and obtaining faster approval for high-quality therapies. However, biologics present unique and time-consuming challenges, such as cell line and analytical development, biological instability, scale-up and limited capacity, which can negatively impact time to market and financial results. Here are 5 steps to create a successful strategy that will help accelerate the time to a robust and reliable...
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Empowering Therapies for Rare Diseases: OLIGOFASTX project

In a world where medical solutions are constantly evolving, OLIGOFASTX emerges as a beacon of hope for those battling rare diseases with no existing treatments. This groundbreaking project spearheaded by our CDMO aims to revolutionize therapy development, paving the way for novel oligonucleotide-based treatments like antimiRNAs, siRNAs, and aptamers. With OLIGOFASTX, we’re not just creating therapies – we’re shaping a future where patients have access to life-changing treatments th...
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Conquering Delta: Our mRNA Vaccine Mission

Amidst the evolving landscape of the COVID-19 pandemic, our company has embarked on an essential project named STABVAC4COV. This groundbreaking initiative aims to develop mRNA-based vaccines tailored specifically to combat the highly transmissible Delta variant of SARS-CoV-2. With the main objective of creating an effective preventive measure against the Delta variant, our dedication to innovation and public health shines brighter than ever. Join us on this critical journey towards a safer, heal...
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Why is Pichia Pastoris a good alternative for the production of recombinant proteins?

Pichia pastoris is a methylotrophic yeast belonging to the class Ascomycetes. Found in the 1960s, its main characteristic is to use methanol as a carbon and energy source. After years of study, P. pastoris has become a model organism for genetic study, being important in the field of biological and biotechnological research. Pichia pastoris is a yeast currently widely used as an expression system for the production of recombinant proteins, both for basic research and industrial purposes,...
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What is the best known living being in the scientific field?

The best known organism in science is certainly a bacterium that lives in the human intestine. Invisible to the naked eye, Escherichia coli is largely responsible for the knowledge of some of the fundamentals of modern biology that have been recognized by several Nobel prizes.  These are the processes of bacterial genetic recombination, RNA transcription, DNA replication and gene regulation. In addition, in recent decades this bacterium has become another tool in the laboratory, especially...
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Vaccines need a supply chain

The long-awaited immunization vaccines for SARS-CoV2 have arrived, and for us all to get back to “normal” again, rapid application and sustained large-scale production are required. On them depends to a large extent to achieve recovery and reduce the economic and human impact that Covid-19 is causing. Generally, vaccines work by exposing to the immune system a virus or part of it, which has been previously weakened or attenuated. When the vaccinated immune system subsequently encounters...
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