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Plasmid DNA Services
Bring your full plasmid DNA program with one responsive CDMO partner. 53Biologics combines GMP and non-GMP capacity, in-house QC and a hands-on team that adapts the path around your project, from E. coli cell banking through manufacturing and Fill & Finish.
3
Quality Grades: Research grade,High-quality and GMP
>95%
successfully released pDNA batches
~11,6
Average staff experience in microbial
Pipeline
One-Stop-Shop for Plasmid DNA Production
pDNA Services
pDNA Cell Banking
Establish a well-characterized and traceable cell bank that provides a consistent biological starting point for plasmid DNA manufacturing. 53Biologics generates, tests and stores E. coli Master and Working Cell Banks under the quality framework your program requires.
pDNA Cell Banking
pDNA Manufacturing
Manufacture pDNA in E. coli at the scale and quality grade your program needs, from Research Grade material to High Quality and GMP supply. 53Biologics supports all needs, with GMP capacity up to 200L and non-GMP production up to 100L.
pDNA Manufacturing
pDNA Analytical Support
From in-process controls to stability studies, our in-house quality control capabilities provide the data needed to confidently advance your pDNA program, minimizing external dependencies at every stage.
pDNA Analytical Support
Fill & Finish
We offer fill & finish solutions across a range of fill volumes and container formats to meet the specific requirements of your product and application. This flexible approach allows us to support all types of projects ensuring the right configuration for your manufacturing needs.
Fill & FinishResearch-grade plasmids
Best suited for: R&D and early preclinical applications
High quality plasmids
Best suited for: Preclinical and toxicology studies
GMP Plasmids
Best suited for: Clinical and GMP applications
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Why Choose 53Biologics for
Plasmid DNA Production?
Partnership That Stays Close
Your scientists work directly with the team running your program, enabling faster progress, open communication and a collaborative way of working from start to finish.
Scientific Confidence
Our expertise helps reduce technical uncertainty. But it also supports informed decisions throughout development and manufacturing, giving your program a stronger foundation for success.
Built Around Your Program
Every plasmid DNA program is different. We adapt our approach, timelines and technical strategy to your molecule, your objectives and the stage of development.
A Partner for Long-Term Supply
From early development to clinical manufacturing, we help create a reliable supply strategy that can evolve with your program while maintaining continuity as your needs grow.
Request a Quote for Your pDNA Program
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