Our experts in Upstream and Downstream can develop a robust and reproducible process
Our flexible facility is specifically designed to adapt the process development to the characteristics of your protein and expression system, accelerating the timelines from pre-clinical concept to manufacturing and reducing risks and costs.
proteins
Our team combines in-depth protein scientific knowledge with a lot of process development expertise having increased productivity in 98% of our projects
Whether your project requires full upstream process development from scratch or only its optimisation, we will design a customized development approach. We have succesfully develop processes for antibodies, biosimilars, growth factors, molecular biology reagents, virus like particles and vaccines.
Our wide experience working with different microbial and mammalian expression systems ensure the best expertise to increase productivity and growth performance for your recombinant protein. Different fermentation scales from 1 to 30 liters with different configurations (i.e. Stirred, wave-induced motion, etc.) and different industrial solutions like glass, stainless steel, single-use bioreactors, etc. are available. Consult our facilities.
We develop customized downstream processes according to the characteristic of your protein and its intended use. Our team has extensive experience developing purification schemes enabling them to overcome purification problems for a wide variety of proteins, soluble or insoluble, whether they are produced in the periplasm, cytoplasm or into inclusion bodies.
Our tailored approach, combined with our state-of-art equipment are used for developing an efficient, robust, and scalable process development to make the leap from pilot scale to manufacturing.
We have the ability to solve complex problems that arise during process development and for this reason, we dare to take on protein projects that not fit into the standards
Discover more about 53Biologics protein services
Strain & Cell Line Development
Cell Banking
Protein Manufacturing
Analytical Services
