Process Development

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We offer complete both upstream and downstream process development support for any plasmid DNA production project.
We provide our best experiences and the most advanced technology to design tailor-made projects for the development of your pDNA. Depending on the pDNA specifications and on the specific project needs we provide the proper solution in a flexible and efficient way.

Our Process Development Solutions

Whatever your quality grade, our solutions include:
  • Microbial scalable production
  • Optimal pDNA clarification systems that separate impurities from even the highest density cell lysates
  • Customized concentration/diafiltration for large and sensitive molecules
  • Efficient and gentle removal of impurities to prevent their degradation
  • We perform efficient and robust polishing chromatographies that reliably produce homogeneous pDNA extracts
  • Our services provide pDNA at the purity you need
  • We conduct sterile filtrations to avoid microbial contamination
  • Throughout the entire pDNA purification process we perform quality control analyses to ensure the robustness of the product

We provide our best experiences and the most advanced technology to design tailor-made projects for your pDNA project development

Discover more about our pDNA Services

Cell Banking

53Biologics is able to construct, characterize and store the cell banks for our customers.

Contract Manufacturing

Our team can provide custom plasmid production that fits your project specifications.

Analytics

Our pDNA services comes with outstanding quality control and documentation support as requested.

Let’s talk about your pDNA process development needs